Publications scientifiques

La création, la diffusion et l’utilisation des savoirs constitue par conséquent une mission clé de la fondation. Vous trouverez ici un aperçu des publications scientifiques.

Safety-relevant medication processes in Swiss nursing homes

Reducing adverse drug events in nursing homes is a central patient safety concern. The aim of this study was to assess how often selected medication processes to increase medication safety are already implemented in Swiss nursing homes and to examine how nursing homes that have not yet implemented these processes can be characterized based on their organizational features.


420 of 1,525 invited individuals participated in the survey (response rate: 27.5 %). Of these, 65.0 % stated that regular systematic medication reviews have been provided in their institution. 9.5 % of the nursing homes use a list to identify potentially inappropriate medication, and 6.7 % of the nursing homes have a standardized process to monitor side effects of medications. 66.0 % of the participating nursing homes have implemented at least one of these three processes, 34.0 % of the participating nursing homes have not implemented any of the three processes. Statistically significant differences in process implementation were found according to the geographical location of the nursing home, the type of documentation used for medications, the physician model, the number of external general practitioners, as well as the medication supply channel and the legal obligation to cooperate with pharmacists. No differences were found with regard to the nursing home size.

In Swiss nursing homes, central safety-relevant medication processes have not yet been implemented nationwide. In particular, implementation is not widespread in nursing homes where medical care for their residents is provided by many different external general practitioners. The organizational features need to be taken into account to successfully implement quality improvement measures.

The journal of evidence and quality in health care

Andrea Niederhauser, Dr. Lea Brühwiler, Dr. Liat Fishmann, Prof. Dr. David Schwappach der Stiftung Patientensicherheit Schweiz.


Patient safety hazards resulting from information technology usage in outpatient oncology infusion centers

The aim of the present study from Dr. Yvonne Pfeiffer, Chantal Zimmrmann and Prof. Dr. David Schwappach from Patient Safety Switzerland was to identify patient safety hazards coming with the use of health information technology (HIT): patient safety hazards in three outpatient oncology infusion centers were assessed and priority topics identified.

Additionally, the number of information sources clinicians have to use in order to get an idea of the patient's situation was systematically assessed. Interviews and observations were conducted with one nurse and one doctor of each ambulatory infusion center.

Principal results
Information management-related patient safety hazards were omnipresent in daily care: eleven topics were identified from 125 assessed patient safety hazards. Three of them were particularly relevant to the clinicians’ development of an adequate mental model about the patient: patient-related information was not stored in one place but often fragmented in different HIT systems; despite the introduction of HIT, paper documentation remained in place for certain information, making access difficult and increasing the number of relevant sources; the lack of usability of the HIT systems made it difficult to retrieve patient information in a timely manner. Clinicians needed to use between 5 and 11 sources of information to get a more complete picture of a patient's situation.

Major conclusions
Overall, it has been shown that the design of the HIT systems is not sufficiently adapted to the work processes and does not support clinicians in being fully informed about a patient. The topics identified point to future system design and areas for improvement. In this process, it is very important to align the real work requirements with the design of the HIT and to evaluate and monitor the actual implementation and use of HIT.

Source: ZEFQ Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen

Authors: Dr. Yvonne Pfeiffer, Chantal Zimmermann, Prof. Dr. David Schwappach, Fondation sécurité des patients suisse


Safe vincristine use in Switzerland: Still a long way to go?

Different international organizations recommend safety measures for the use of vincristine to prevent wrong route administrations. A central recommendation is to use infusion bags instead of syringes to prevent confusion with intrathecal chemotherapy. This study aimed to investigate the implementation of safety measures for vincristine and intrathecal chemotherapies in Switzerland.

Source:  Journal of Oncology Pharmacy Practice

Authors: Dr Lea Brühwiler et Prof. Dr David Schwappach, Fondation Sécurité des patients Suisse


Patient Safety in Cancer Care

Cancer care has seen large successes in terms of increased survival rates and improvements in quality of life. However, despite these achievements, many patients suffer preventable harm from treatment. Studies of patient safety in cancer care have usually focused on chemotherapy safety and have been conducted in large centers. These studies reveal that errors are more frequent in more complex therapies and that about 1-3% of adult and pediatric patients are affected by chemotherapy errors 1.

Source: eonsmagazine Winter/Spring 2019

Author: Prof. Dr. David Schappach, Directeur recherche et développement, Directeur adjoint, Fondation sécurité des patients Suisse

Speaking Up about Patient Safety in Perioperative Care: Differences between Academic and Nonacademic Hospitals in Austria and Switzerland

Purpose of the Study: In perioperative care, communication about patient safety concerns is both difficult and valuable. Research into speaking up has mostly been conducted in single countries; the aim of this study was to compare speaking up-related climate and behaviors in academic and nonacademic hospitals.

Source: Journal of Investigative Surgery


David Schwappach from Swiss Patient Safety Foundation, Zurich, Switzerland
Gerald Sendlhofer from Executive Department for Quality and Risk Management, Landeskrankenhaus-Universitatsklinikum Graz, Graz, Austria and Division of Plastic, Aesthetic and Reconstructive Surgery, Department of Surgery, Research Unit for Safety in Health, Medizinische Universitat Graz, Graz, Austria


Assessment of the safety climate in outpatient diagnostic services: Development and psychometric evaluation of a questionnaire

Safe practice and safety culture are important issues in outpatient diagnostic imaging services. As questionnaires assessing safety culture through the measurement of safety climate in this setting are not yet available, the present study aimed to develop and validate such an instrument.



The final instrument presents a valid, consistent and reliable option to measure safety climate in outpatient diagnostic imaging services. Results can be used as a basis for quality improvement.

Key Points

• An adapted questionnaire that assesses safety climate in outpatient diagnostic imaging services was developed and tested in Switzerland.

• Psychometric evaluation showed the questionnaire to be a valid, consistent and reliable instrument.

• Results are of interest for imaging services as well as for stakeholders interested more globally in monitoring and quality improvement


Marianne Jossen, Fabio Valeri, Christina Heilmaier, David Schwappach

Springer Link, European Radiology



Medication safety in Switzerland: Where are we today?

Empirical research shows that medication safety is an urgent area of concern in the Swiss healthcare system. Adverse drug events and medication errors are common and risks such as polypharmacy are widespread.


No comprehensive national strategy explicitly dedicated to medication safety exists in Switzerland. The federalist system of government with relative autonomy of the cantons relating to healthcare laws influences the implementation of national healthcare reforms, also to the disadvantage of medication safety. Direct dispensing of drugs by the prescribing physician is permitted in almost all German-speaking cantons. This special feature of the Swiss system implies specific challenges for medication safety. Nonetheless, there is an increasing number of national activities dealing with various aspects of medication safety, such as the “progress!” programmes within the National Quality Strategy. Within the National Research Programme “Smarter Health Care” (NRP 74) of the Swiss National Science Foundation, several research projects are currently focusing on medication safety. Clinical pharmacy activities in hospitals are relatively widespread. In the primary care sector, pharmaceutical care practice and the corresponding competencies for pharmacists are being further developed. However, a comprehensive strategy, priority-setting and effectiveness studies involving all stakeholders are required in order for the Swiss healthcare system, to meet the challenges facing medication safety in a forward-looking manner.

Liat Fishman, Lea Brühwiler, David Schwappach

Springer Link/Bundesgesunheitsblatt - Gesundheitsforschung - Gesundheitsschutz


Nurses’ and Physicians’ Perceptions of Indwelling Urinary Catheter Practices and Culture in Their Institutions

Objectives Indwelling urinary catheters (IUCs) are commonly used devices in acute care that may lead to catheter-associated urinary tract infections or noninfectious complications. Responsibilities for IUC are usually shared between nurses and physicians, and a common mental model among the two professional groups is thus essential for a successful reduction in catheter use. The aim of this study was to determine variation in the perceptions of current practices and culture regarding IUC use between these two groups.


Nurses and physicians each have their own tasks but also share responsibilities for catheter placement, care, and removal. Overall, nurses were more positive than physicians about current practices and culture regarding IUC use within their institution (mean scale scores = 5.4 for nurses versus 5.1 for physicians, P < 0.001). Perceptions of the two professional groups diverged most strongly on practices to avoid unnecessary placement of IUCs, the presence of shared values and attitudes in support of restrictive catheter use, and the other group's leadership commitment.



Niederhauser, Andrea, MPH*; Züllig, Stephanie, PhD*; Marschall, Jonas, MD†‡; Schwappach, David LB, PhD*§ progress! Safe Urinary Catheterization Collaboration Group

Implications of involving pharmacy technicians in obtaining a best possible medication history from the perspectives of pharmaceutical, medical and nursing staff: a qualitative study

Andrea Niederhauser, Chantal Zimmermann, Liat Fishman, David L B Schwappach, BMJ Open 2018;8:e020566. doi:10.1136/bmjopen-2017-020566

Speaking up behaviors and safety climate in an Austrian university hospital

Schwappach DLBS, Sendlhofer G, Häsler L, Gombotz V, Leitgeb K, Hoffmann M, Jantscher L, Brunner G, International Journal for Quality in Health Care 2018. Doi: 10.1093/intqhc/mzy089

Speak up-related climate and its association with healthcare workers’ speaking up and withholding voice behaviours: a cross-sectional survey in Switzerland

Schwappach DLB, Richard A, BMJ Quality & Safety 2018. Doi: 10.1136/bmjqs-2017-007388

Medication Safety in Oncology Care: Mapping Checking Procedures From Prescription to Administration of Chemotherapy

Pfeiffer YP, Gut SS, Schwappach DLB, Journal of Oncology Practice 2018; Doi: 10.1200/JOP.2017.026427

Oncology nurses‘ beliefs and attitudes towards the double-check of chemotherapy medications: a cross-sectional survey study

Schwappach DLB, Taxis K, Pfeiffer Y, BMC Health Services Research 2018. Doi: 10.1186/s12913-018-2937-9

Implementation status of morbidity and mortality conferences in Swiss hospitals: a national cross-sectional survey study

Isabelle Praplan-Rudaz, Yvonne Pfeiffer, David L B Schwappach, International Journal for Quality in Health Care 2018; doi: 10.1093/intqhc/mzx204

Morbidity and mortality conferences (M&MCs) in Switzerland are widely used to promote medical education, patient safety and quality improvements. However, the term M&MC seems to cover different types of meetings. Although the overall goals are similar, various types of M&MCs are used in practice and different objectives are pursued. Tools such as checklists, guidelines and templates are considered helpful.

Chief physicians’ perceived need for improvement of morbidity and mortality conferences: the role of structural and procedural characteristics.

David L B Schwappach, Lynn Häsler, Yvonne Pfeiffer, BMJ Leader 2018; doi: 10.1136/leader-2017-000052

Chief physicians' attitudes towards early warning score systems in Switzerland: Results of a cross‐sectional survey

Aline Richard, Olga Frank, David Schwappach, Eval Clin Pract. 2017;1–7.

Development and Psychometric Evaluation of the Speaking Up About Patient Safety Questionnaire

Richard, Aline PhD; Pfeiffer, Yvonne PhD; Schwappach, David D.L. PhD, Journal of Patient Safety: August 28, 2017


Patient safety climate profiles across time: Strength and level of safety climate associated with a quality improvement program in Switzerland: A cross-sectional survey study

Anna C. Mascherek, David L. B. Schwappach, PLOS ONE

Patient safety priorities in mental healthcare in Switzerland: a modified Delphi study

Anna C Mascherek, David L B Schwappach, BMJ Open 2016;6:e011494. doi:10.1136/bmjopen-2016-011494

Surgical checklist use in Switzerland 2015 – where are we today?: a cross-sectional national survey study

Anna C. Mascherek, David L. B. Schwappach, Safety in Health (2016) 2:6, DOI 10.1186/s40886-016-0017-6